OC 203/CD 213(AUG) 3:0
Electronic effects in organic compounds, aromaticity, frontier orbital theory, steric
effects, stereochemistry, conformational analysis. Methods of deducing
organic reaction mechanisms,
S Chandrasekhar and Uday Maitra
Smith, M.B., March J., March’s Advanced Organic Chemistry: Reactions, Mechanisms and Structure, Sixth Edn, Wiley, 2007.
Carey, F.A., and Sundberg, R.J., Advanced Organic Chemistry, Part A, Fourth Edn, Plenum, 2001.
Lowry, T.M., and Richardson, K.S., Mechanism and theory in Organic Chemistry, Third Edn, Harper and Row, 1986.
OC 231 (AUG) 3:0
Chemistry of Biological Systems
Molecules of nature: amino acids, nucleic acids, lipids, carbohydrates. Mechanism of action of selected enzymes and coenzymes, enzyme inhibition. Concepts of biological cell, membranes and their components. Different membranous properties, phase-transition, lipid motions, transport in membranes, molecular biology, chemistry of nucleic acid, DNA synthesis, cloning and use of recombinant DNA technology, proteins, immunochemistry, catalytic antibodies. Other important developments in current literature. Requirements include submission of a term paper on a topic current literature and presentation of a seminar.
S Bhattacharya and E
Voet, D., and Voet, J.G., Biochemistry, Second Edn,
Stryer, L., Biochemistry, Fourth Edn, W H Freeman & Co., NY.
OC 301 (AUG) 3:0
Advanced Organic Synthesis
Planning and synthesis, retrosynthetic analysis-disconnection approach, convergent synthesis, linear synthesis-protecting groups-ring forming strategy-umpolung synthesis- synthesis of natural products. Recent literature in total synthesis of natural products.
Kavirayani R Prasad
Corey, E.J., and Cheng, X., The Logic of chemical
Warren, S., Organic Synthesis: The Disconnection Approach, Wiley NY, 1982.
Apsimon, Total Synthesis of Natural Products, Vol. I-IX Wiley Interscience.