Integrated PhD (Chemical Sciences)

 


Course Work

 

Core Courses

 

Course Credits Course Title

 

CD 203 3:0        Group Theory and Molecular Spectroscopy

CD 211 3:0        Physical Chemistry-I

CD 212 3:0        Inorganic Chemistry-I

CD 213 3:0        Organic Chemistry-I

CD 214 3:0        Basic Mathematics

CD 215 0:4        General Chemistry Lab.

                        (Organic & Inorganic)

CD 221 3:0        Physical Chemistry II:

                        Quantum Chemistry and

                        Statistical Mechanics

CD 222 3:0        Material Chemistry

CD 223 3:0        Organic Synthesis

CD 224 2:1        Computers in Chemistry

CD 225 0:4        Physical and Analytical

                        Chemistry Lab.

CD 232 3:0        Electronics for Scientists

CD 301 3:0        Two–Dimensional NMR

                        Spectroscopy

CD 311 3:0        Bioinorganic & Organo-

                        metallic Chemistry

 

Project

 

CD 241 0:10 Project

 

Research Project

Elective Courses: 15 credits (including two 300 level courses)

 

Note: Elective Courses are to be selected from the courses in the Division of Chemical Sciences. Students may also select courses offered in other Divisions of the Institute in consultation with their supervisor or the coordinator of the programme in the Division of Chemical Sciences.

 

 

CD 203/IP 203  (AUG) 3:0

Group Theory and Molecular Spectroscopy

 

Group theory: symmetry elements and operations, products of operations, point groups, matrices and representations, reducible and irreducible character tables, great orthogonality theorem, direct product of irreducible representation. Time dependent states and spectroscopy: time dependent perturbation theory, absorption and emission of radiation, selection rules, line shapes and widths, lasers. Vibrations and rotations of diatomic molecules: nuclear motion in diatomics, anharmonicity, vibration-rotation interaction, potential energy functions, selection rules, rotational spectra, rovibrational spectra. Vibrations of polyatomic molecules. Classical mechanics of vibrations, symmetry and normal vibrations, IR and Raman spectroscopy techniques including resonance Raman. Electronic spectroscopy: diatomic molecules, coupling of electronic and rotational angular momentum, analysis of vibronic and rovibronic spectra, electronic spectra of polyatomic molecules, molecular orbitals and electronic states, electronic and vibronic selection rules, multi-photon spectroscopy. Magnetic resonance: NMR and ESR spectroscopy. Experimental methods and applications. Structure determination, 2D NMR, NMR of solids.

 

S Umapathy and E Arunan

 

Levine, I., Molecular Spectroscopy, A Wiley Interscience Publications

Hollas, J.M., Molecular Spectroscopy, A Wiley Interscience Publications

 

CD 211 (AUG) 3:0

Physical Chemistry – I: Thermodynamics, Kinetics and Electrochemistry

 

Intermolecular forces: van der Waal’s interactions, Lennard-Jones potentials, Stockmayer potential, hydrogen bonding. Thermodynamics: the three laws, free energies and chemical potentials, applications to electrochemistry, thermodynamic properties of liquids and solids, changes of phase. Chemical reaction dynamics: rate processes in chemistry, activated complex theory, photochemical reactions, chain reactions oscillatory reactions, catalysis.

 

N Munichandraiah and P K Das

 

Mcquarrie, D.A., and Simon, J.D., Physical Chemistry: A Molecular Approach, Viva Books, New Delhi, 1998.

 

CD 212 (AUG) 3:0

Inorganic Chemistry -I

 

VSEPR and molecular structure, understanding periodic properties. Main group chemistry: hydrogen and its compounds, the boron and the carbon groups, the nitrogen and the oxygen groups, the halogens and noble gases. Coordination chemistry: bonding theories, magnetic and electronic spectral properties. Inorganic reactions and mechanisms: hydrolysis reactions, trans-effect, isomerisation reactions, redox reactions, and mixed-valence systems. Chemistry of lanthanides and actinides.

 

B R Jagirdar and P Thilagar

 

Shriver, D.F., Atkins, P.W., and Langford, C.H., Inorganic Chemistry, Freeman, NY, 1990.

Cotton, F.A., and Wilkinson, G., Advanced Inorganic Chemistry, Fifth Edn, John Wiley, NY, 1987.

Huheey, J.E., Inorganic Chemistry: Principles of Structure and Reactivity, Harper Intl, Third Edn, 1983.

 

CD 213 (AUG) 3:0

Organic Chemistry I

 

Important electronic effects in organic compounds, aromaticity, frontier orbital theory, steric effects, stereochemistry, conformational analysis. Methods of deducing organic reaction mechanisms, Hammond postulate, Curtin-Hammett principle, linear free energy relationship, Hammett and Taft equations. Organic transformations and molecular rearrangements. Reactive intermediates, classical and non-classical carbocations, carbanions, free radicals, carbenes, nitrenes, arynes, radical ions, diradicals, concerted reaction, Woodword-Hoffmann rules.

 

Uday Maitra and Sosale Chandrasekhar

 

March, J., Advanced Organic Chemistry, Third Edn, Wiley, 1985.

Carey, F.A., and Sundberg, R.J., Advanced Organic Chemistry, Part A, Second Edn, Plenum, 1984

Lawry, T.M., and Richardson, K.S., Mechanism and Theory in Organic Chemistry, Third Edn. Harper & Row, 1986.

 

CD 214 (AUG) 3:0

Basic Mathematics

 

Differentiation and integration, different methods of evaluating integrals, multi-dimensional integrals, numerical integration. Vectors – gradient, divergence and curl, and their physical significance. Matrices – eigenvalues and eigenvectors. Complex variables, Cauchy-Reimann conditions, Cauchy’s theorem, Cauchy’s integral formula. Differential equations, differential equations of quantum chemistry and chemical kinetics, numerical solutions of differential equations. The Dirac delta function, the gamma and error function. Function spaces, orthonormal functions, Fourier series, Fourier and Laplace transforms, fast Fourier transforms.

 

N Suryaprakash and H S Atreya

 

Thomas, G.B., and Finney, R.L., Calculus and Analytical Geometry, Narosa Publishing, 1984.

Arfken, G.B., and Weber, H.J., Mathematical Methods for Physicists, Prism Indian Edn, 1995.

Keryszig, E., Advanced Engineering Mathematics, Wiley Eastern Limited, 1983.

 

CD 215 (AUG) 0:4

Organic & Inorganic Chemistry Laboratory

 

Common organic transformations such as esterification, Diels-Alder reaction, oxidation-reduction, Grignard reaction, etc. Isolation and purification of products by chromatographic techniques, characterization of purified products by IR and NMR spectroscopy. Synthesis of coordination complexes, preparation of compounds of main group elements, synthesis of organometallic complexes. Physico-chemical characterization of these compounds by analytical and spectroscopic techniques.

 

N Jayaraman and P S Mukherjee

 

Vogel’s Qualitative Inorganic Analysis

 

CD 221 (JAN) 3:0

Physical Chemistry II: Quantum Chemistry and Statistical Mechanics

 

Quantum mechanics: postulates, measurements, operators, exactly solvable problems – particle on a ring, sphere, rigid rotor, harmonic oscillator, hydrogenic atom, approximate methods. Electron, atoms and molecules: independent particle approximation, central field problem, approximate methods for molecules, Huckel model, CNDO and semi-empirical methods, role of electron correlations. Statistical mechanics: ensembles, partition functions, averages, distributions, application to rotational and vibrational problems, specific heats of solids, phase transitions. Dynamics: kinetics and relaxation, diffusion equation, non-equilibrium thermodynamics light scattering. Simulations: configuration averages, central limit theorem, metropolis method, molecular dynamics, simulations of different ensembles.

 

Aninda Bhattacharya

 

Schiff, L.I., Quantum Mechanics, Third Edn, McGraw Hill, 1987.

Callen, H.B., Thermodynamics and Introduction to Thermostatistics, Second Edn, John Wiley, 1985.

 

CD 222 (JAN) 3:0

Material Chemistry

 

Structure of solids, dymmetry concepts, crystal structure. Preparative methods and characterization of inorganic solids. crystal defects and non stoichometry. Interpretation of phase diagrams, phase transitions. Kinetics of phase transformations, structure property correlations in ceramics, glasses, polymers. Composites and nano-materials. Basics of magnetic, electrical, optical, thermal and mechanical properties of solids.

 

Srinivasa Raghavan, K K Nanda and N Ravishankar

 

West, A.R., Solid State Chemistry and its applications,,John Wiley and Sons, 1984.

Shackelford, J.F., Introduction to Materials Science for Engineers, MacMillan, 1988.

 

CD 223 (JAN) 3:0

Organic synthesis

 

Principles of selectivity and reactivity in the use of reagents for oxidation, reduction and bond forming reaction. Planning a synthesis, antithetic analysis, synthons, linear and convergent synthesis.

 

S Chandrasekaran and N Jayaraman

 

Warren, S., Designing Organic Synthesis, John Wiley and Sons, 1978.

Carruthers, W.S., Some Modern Methods of Organic Synthesis, Third Edn, Cambridge Univ. Press, 1986.

Carery, F.A., and Sundberg, R.J., Advanced Organic Chemistry, Part B, Second Edn, Plenum, 1984.

House, H.O., Modern Synthetic Reactions, Benjamin Cummings, 1972.

Fuhrhop, J., and Penzilin, G., Organic Synthesis – Concepts, Methods, Starting Materials, Verlog Chemie, 1983.

 

CD 224 (JAN) 2:1

Computers in Chemistry

 

Number systems: binary, octal, decimal, hexadecimal. Computer architecture, machine language, assembly language programming, algorithms, Fortran 90 and HPF with programming examples from chemistry and other areas. Visualisation. Numerical methods: interpolation, curve fitting, integration, linear algebraic systems, ordinary differential equations and matrix eigenvalue problems. Parallelisation.

 

S Yashonath and A G Samuelson

 

Rajaraman, V., Computer Programming in FORTRAN 90 and 95

Rajaraman, V., and Siva Ram Murthy, C., Parallel Computers – Architecture and Programming.

Chapra, S.C., and Canal, R.P., Numerical Methods for Engineers,

Lewars, E.G., Computational Chemistry: Introduction to the Theory and Applications of Molecular Quantum Mechanics

 

CD 225 (JAN) 0: 4

Physical and Analytical Chemistry Laboratory

 

Chemical kinetics; Langmuir adsorption, chemical analysis by potentiometric and conductometric methods, cyclic voltametry, flame photometry, electronic states by UV-Visible spectroscopy, IR spectroscopy, solid state chemistry – synthesis of solids and chemical analysis, thermogravimetry, X-ray diffraction; electrical and magnetic properties of solids. Vacuum techniques in preparative chemistry.

 

M S Hegde and C Shivakumar

 

Vogel, A.I., Vogel’s text book of quantitative chemical analysis, Longman, 1989.

Shoemaker, D.R., Garland, C.W., and Nibler, J.W., Experiments in Physical Chemistry, McGraw Hill Intl Edn, 1989.

 

CD 232 (AUG) 0:4

Electronics for Chemical Scientists

 

Working principle of transistors and diodes. Design of transistor based amplifiers and power supplies. Using operational amplifiers in designing of temperature controllers, temperature indicators, lock-in amplifiers, pH meters, conductivity meters, battery chargers, power supplies, etc. Basic concepts of digital circuits, designing of display circuits, counters etc. Working principle of microprocessors, A/D and D/A converters.

 

M K Gunasekaran and V Jayaram

 

Horowiz, P., and Hill, W., The Art of Electronics, Second Edn, Cambridge Univ. Press, 1992.

Gaonkar, Microprocessor Architecture Programming and Applications, Wiley Eastern Limited, 1992.

 

CD 241 (JAN) 0:10

Research Project

 

Faculty

 

 

CD 301 (JAN) 3:0

Two-dimensional NMR Spectroscopy

 

Basic principles of two-dimensional (2D) NMR spectroscopy, 2D line shapes phases and filtering. Resolved 2D spectroscopy Correlated 2D experiments (COSY, TOCSY, etc.) involving homo-nuclear and heteronuclear correlations. 2D multiple-quantum spectroscopy 2D relaxation experiments (NOESY, ROESY). Multinuclear 2D and 3D experiments such as HSQC, HMQC, HNCA and HNCA (CO) etc. Introduction to coherence level diagram, product operator formalism, phase cycling and gradient-enhanced spectroscopy. Two-dimensional NMR of solids. NMR imaging. Applications of two and three-dimensional NMR experiments for structure determination of large molecules.

 

N Suryaprakash, S Raghothama and H S Atreya

 

Croasmun, W.R., and Carlson, R.M.K., Two-Dimensional NMR Spectroscopy – Applications for Chemists and Biochemists, VCH, 1987.

Martin, G.E., and Zektzer, A.S., Two-dimensional NMR Methods for establishing Molecular Connectivity: A chemists’ Guide to experiment selection, performance and interpretation, VCH, 1988.

 

 

CD 311/IP 311 (AUG) 3:0

Bioinorganic & Organometallic Chemistry

 

Principles of coordination chemistry related to bioinorganic chemistry; properties of biological molecules; structural and functional aspects of metalloproteins; photosynthesis; alkali and alkaline earth metals in biological systems; medicinal aspects of bioorganic chemistry. Structure and bonding in organometallic compounds; isolobal analogies, metal carbonyls, metallocenes. Major reaction types; oxidative addition, reductive elimination, insertion, isomerization and rearrangement reactions. Catalytic reactions.

 

G Mugesh and A G Samuelson

 

Lippard, S.J., and Berg, J.M., Principles of Bioorganic Chemistry, University Science Books, California, 1994.

Elschenbroich, Ch. and Salzer, A., Organometallics, Second Edn, VCH, Weinheim, 1992.

Crabtree, R.H, The Organometallic Chemistry of the Transition Metals, Second Edn, John Wiley.

Albright, T.A., Burdett, J.K., and Whangoo, M.-H., Orbital Interactions in Chemistry, John Wiley, New York 1985.

Collman, J.R., and Hegedus, L.S.L., Principles and Applications of Organotransition Metal Chemistry, University Science Books, California, 1987.